Etimizol

Etimizol (Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain) . Etimizol can decrease the K-+ permeability of neurons' membrane during action potential.

Product Specifications

CAS Number

[64-99-3]

Product Name Alternative

Ethimizole; Ethymisol; Ethymisole

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/etimizol.html

Concentration

10mM

Purity

99.88

Solubility

Ethanol : ≥ 33.33 mg/mL

Smiles

O=C(C1=C(C(NC)=O)N(CC)C=N1)NC

Molecular Formula

C9H14N4O2

Molecular Weight

210.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Borisova GIu. Effect of etimizol on instrumental learning in rats. Biull Eksp Biol Med. 1985 Jun;99 (6) :705-6.|[2]Trnovec T, et al. Etimizol absorption from the small intestine in dogs: the dependence on dosage. Biull Eksp Biol Med. 1986 Dec;102 (12) :729-30.|[3]Vislobokov AI, et al. Elektrophysiological parameters of mollusk neurons under the influence of etimizol. Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61 (6) :917-24.