Mc-MMAD

Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC.

Product Specifications

CAS Number

[1401963-15-2]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Mc-MMAD.html

Purity

98.39

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1N(CCCCCC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)CCC2)=O)OC)=O)=O)C(C)C)=O)C(C=C1)=O

Molecular Formula

C51H77N7O9S

Molecular Weight

964.26

References & Citations

[1]Antibody-drug conjugates Patent: WO 2013068874 A1

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Auristatin

Available Sizes

Curated Selection

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