FEN1-IN-5

FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].

Product Specifications

CAS Number

[824983-93-9]

UNSPSC

12352005

Target

FLAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fen1-in-5.html

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=C(N(CC3=CC=CC(C4=CC=CC(NC(C)=O)=C4)=C3)C(N1O)=O)C=CS2

Molecular Formula

C21H17N3O4S

Molecular Weight

407.44

References & Citations

[1]Wadhwa P, et al. QSAR and Docking Studies of N-hydroxy Urea Derivatives as Flap Endonuclease-1 Inhibitors. Curr Comput Aided Drug Des. 2015;11 (4) :346-52.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-47819DL594 0.1 mL

Mouse Monoclonal Caldesmon/CALD1 Antibody (CALD1/820 + h-CALD) [Dylight 594]

Ask

View Details

MBS9214710-01 0.08 mL

TTC33 Antibody

Ask

View Details

MBS9214710-02 0.4 mL

TTC33 Antibody

Ask

View Details

MBS9214710-03 5x 0.4 mL

TTC33 Antibody

Ask

View Details

GWB-F9D968 0.05 mg

MCM2 Antibody

Ask

View Details

244656-AP 100 µL

CHD8 (Chromodomain Helicase DNA Binding Protein 8, DKFZp686N17164, HELSNF1, KIAA1564) (AP) discontinued

Ask

View Details