FEN1-IN-5
Product Specifications
UNSPSC Description
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].
Target Antigen
FLAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fen1-in-5.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(CC3=CC=CC(C4=CC=CC(NC(C)=O)=C4)=C3)C(N1O)=O)C=CS2
Molecular Weight
407.44
References & Citations
[1]Wadhwa P, et al. QSAR and Docking Studies of N-hydroxy Urea Derivatives as Flap Endonuclease-1 Inhibitors. Curr Comput Aided Drug Des. 2015;11(4):346-52.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153790/FEN1-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153790/FEN1-IN-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
824983-93-9
Available Sizes
Curated Selection
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