FEN1-IN-5

FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].

Product Specifications

CAS Number

[824983-93-9]

UNSPSC

12352005

Target

FLAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fen1-in-5.html

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=C(N(CC3=CC=CC(C4=CC=CC(NC(C)=O)=C4)=C3)C(N1O)=O)C=CS2

Molecular Formula

C21H17N3O4S

Molecular Weight

407.44

References & Citations

[1]Wadhwa P, et al. QSAR and Docking Studies of N-hydroxy Urea Derivatives as Flap Endonuclease-1 Inhibitors. Curr Comput Aided Drug Des. 2015;11 (4) :346-52.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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