FEN1-IN-5
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].
Product Specifications
CAS Number
[824983-93-9]
UNSPSC
12352005
Target
FLAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fen1-in-5.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(CC3=CC=CC(C4=CC=CC(NC(C)=O)=C4)=C3)C(N1O)=O)C=CS2
Molecular Formula
C21H17N3O4S
Molecular Weight
407.44
References & Citations
[1]Wadhwa P, et al. QSAR and Docking Studies of N-hydroxy Urea Derivatives as Flap Endonuclease-1 Inhibitors. Curr Comput Aided Drug Des. 2015;11 (4) :346-52.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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