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Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114)

Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse MHC Class II. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) reacts with mouse MHC Class II haplotypes I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) does not react with I-Af, I-Ak, or I-As haplotypes. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) blocks MHC Class II and inhibit T cell generation. Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) can be used for the researches of infection and immunology, such as influenza A virus (IAV) infection[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Influenza Virus; MHC

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-mhc-class-ii-i-a-i-e-antibody-m5-114.html

Purity

99

Solubility

10 mM in DMSO

Smiles

[Anti-MouseMHCClassII(I-A/I-E)Antibody(M5/114)]

Molecular Weight

(150 kDa)

References & Citations

[1]McKinstry KK, et al. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 5;5:5377.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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