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RU-TRAAK-2

RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor. RU-TRAAK-2 exerts no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2) [1]. RU-TRAAK-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

1210538-56-9

Product Name Alternative

GW876167 hydrochloride; BVT-933 hydrochloride,GW876167; BVT-943

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ru-traak-2.html

Purity

99.53

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NCC#CC1=CC=CC=C1)N(CC2=NC3=CC=CC=C3S2)C

Molecular Formula

C19H17N3OS

Molecular Weight

335.42

References & Citations

[1]Su Z, et al. Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A. 2016;113 (20) :5748-5753.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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