Tanogitran
Product Specifications
UNSPSC Description
Tanogitran is a dual inhibitor targeting Factor Xa and thrombin (thrombin), with Ki values of 26 and 2.7 nM, respectively. Tanogitran exhibits anticoagulant activity and can be used for research in thrombotic diseases[1][2].
Target Antigen
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tanogitran.html
Smiles
O=C(N1CCCC1)[C@@](C)(C2=CC=C(N(C(CNC3=CC=C(C=C3)C(N)=N)=N4)C)C4=C2)NCC(O)=O
Molecular Weight
477.56
References & Citations
[1]Gómez-Outes A, et al. New parenteral anticoagulants in development. Ther Adv Cardiovasc Dis. 2011 Feb;5(1):33-59. |[2]Remko M, et al. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2):185.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10725/Tanogitran-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10725/
Clinical Information
Phase 1
CAS Number
637328-69-9
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