IGF-1R/SRC-IN-1

IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1].

Product Specifications

CAS Number

[852367-46-5]

UNSPSC

12352005

Target

IGF-1R; Src

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/igf-1r-src-in-1.html

Purity

99.86

Solubility

DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C)C=C3

Molecular Formula

C18H16N2O2

Molecular Weight

292.33

References & Citations

[1]Schmidt S, et al., Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2- (1H-indol-3-yl) -2-oxoacetohydrazide structure. Eur J Med Chem. 2011 Jul;46 (7) :2759-69.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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