IGF-1R/SRC-IN-1
IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1].
Product Specifications
CAS Number
[852367-46-5]
UNSPSC
12352005
Target
IGF-1R; Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/igf-1r-src-in-1.html
Purity
99.86
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C)C=C3
Molecular Formula
C18H16N2O2
Molecular Weight
292.33
References & Citations
[1]Schmidt S, et al., Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2- (1H-indol-3-yl) -2-oxoacetohydrazide structure. Eur J Med Chem. 2011 Jul;46 (7) :2759-69.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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