IGF-1R/SRC-IN-1
Product Specifications
UNSPSC Description
IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1].
Target Antigen
IGF-1R; Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/igf-1r-src-in-1.html
Solubility
DMSO : 31.25 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C(C1=CNC2=C1C=CC=C2)=O)NCC3=CC=C(C)C=C3
Molecular Weight
292.33
References & Citations
[1]Schmidt S, et al., Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide structure. Eur J Med Chem. 2011 Jul;46(7):2759-69.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156914/IGF-1R-SRC-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156914/IGF-1R-SRC-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
852367-46-5
Available Sizes
Curated Selection
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