Guaifenesin
Product Specifications
UNSPSC Description
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].
Target Antigen
Mucin
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Guaifenesin.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic;warming)
Smiles
OCC(O)COC1=CC=CC=C1OC
Molecular Weight
198.218
References & Citations
[1]Bennett, S., N. Hoffman, and M. Monga, Ephedrine- and guaifenesin-induced nephrolithiasis. J Altern Complement Med, 2004. 10(6): p. 967-9.|[2]Dicpinigaitis PV, et, al. Effect of guaifenesin on cough reflex sensitivity. Chest. 2003 Dec;124(6):2178-81.|[3]Seagrave J, et al. Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells. Exp Lung Res. 2011 Dec;37(10):606-14.|[4]Seagrave J, et al. Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells. Respir Res. 2012 Oct 31;13(1):98.|[5]Kagan L,et al. Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model. Pulm Pharmacol Ther. 2009 Jun;22(3):260-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0264/Guaifenesin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0264/Guaifenesin-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
93-14-1
Available Sizes
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