Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Withaferin A (Standard)

Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.

Product Specifications

CAS Number

5119-48-2

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Ferroptosis; NF-κB; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; NF-κB; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/withaferin-a-standard.html

Purity

99.81

Smiles

C[C@]([C@](CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@@H]([C@@](O3)([H])CC(C)=C(CO)C3=O)C)([H])[C@@]2([H])C4)(C(C=C5)=O)[C@@]6([C@H]5O)[C@@H]4O6

Molecular Formula

C28H38O6

Molecular Weight

470.60

Precautions

H315, H319, H335

References & Citations

[1]Kaileh M, et al. Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. J Biol Chem. 2007 Feb 16;282 (7) :4253-64. Epub 2006 Dec 6.|[2]Bargagna-Mohan P, et al. The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin. Chem Biol. 2007 Jun;14 (6) :623-34.|[3]Kakar SS, et al. Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells. Oncotarget. 2017 Aug 10;8 (43) :74494-74505.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Beta Catenin (p120) (Rabbit PAb), 0.2mg/mL
BNUB0376-100 1x 100 µL

Beta Catenin (p120) (Rabbit PAb), 0.2mg/mL

Sign In for Pricing
View Details
Human BMP-2 Antibody Pair Set
E-KAB-0159 50 µL & 100 µg

Human BMP-2 Antibody Pair Set

Sign In for Pricing
View Details
Mouse Peroxisome Proliferator Activated Receptor Delta (PPARd) ELISA Kit
RD-PPARd-Mu-01 96 Tests

Mouse Peroxisome Proliferator Activated Receptor Delta (PPARd) ELISA Kit

Sign In for Pricing
View Details
Mouse Peroxisome Proliferator Activated Receptor Delta (PPARd) ELISA Kit
RD-PPARd-Mu-02 48 Tests

Mouse Peroxisome Proliferator Activated Receptor Delta (PPARd) ELISA Kit

Sign In for Pricing
View Details
CD43 (84-3C1), Biotin conjugate, 0.1mg/mL
BNCB0342-100 1x 100 µL

CD43 (84-3C1), Biotin conjugate, 0.1mg/mL

Sign In for Pricing
View Details
3-Hexyne
TRC-H325240-250MG 250 mg

3-Hexyne

Sign In for Pricing
View Details