Neuromedin N
Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.
Product Specifications
CAS Number
[92169-45-4]
Product Name Alternative
Neuromedin N (rat, mouse, porcine, canine)
UNSPSC
12352209
Target
Dopamine Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Neuromedin-N.html
Concentration
10mM
Purity
99.84
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC2=CC=C(O)C=C2)=O)[C@H]([C@@H](C)CC)NC([C@@H](N)CCCCN)=O
Molecular Formula
C38H63N7O8
Molecular Weight
745.95
References & Citations
[1]Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155 (2) :121-4.|[2]Checler F, et al. Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol. 1986 Jul 31;126 (3) :239-44.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
D2 Receptor
Available Sizes
Curated Selection
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