SR 146131
SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.
Product Specifications
CAS Number
221671-61-0
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/SR_146131.html
Purity
98.23
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)CN1C(C(NC2=NC(C3=CC(OC)=C(Cl)C=C3OC)=C(CCC4CCCCC4)S2)=O)=CC5=C1C(C)=CC(C)=C5
Molecular Formula
C32H36ClN3O5S
Molecular Weight
610.16
References & Citations
[1]Bignon E, et al. SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies. J Pharmacol Exp Ther. 1999 May;289 (2) :742-51.|[2]Bignon E, et al. SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization. J Pharmacol Exp Ther. 1999 May;289 (2) :752-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CCKAR
Available Sizes
Frequently Asked Questions
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