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SR 146131

SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.

Product Specifications

CAS Number

221671-61-0

UNSPSC

12352005

Target

Cholecystokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/SR_146131.html

Purity

98.23

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)CN1C(C(NC2=NC(C3=CC(OC)=C(Cl)C=C3OC)=C(CCC4CCCCC4)S2)=O)=CC5=C1C(C)=CC(C)=C5

Molecular Formula

C32H36ClN3O5S

Molecular Weight

610.16

References & Citations

[1]Bignon E, et al. SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies. J Pharmacol Exp Ther. 1999 May;289 (2) :742-51.|[2]Bignon E, et al. SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization. J Pharmacol Exp Ther. 1999 May;289 (2) :752-61.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

CCKAR

Available Sizes

Frequently Asked Questions

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