Ethambutol-d4 dihydrochloride
Ethambutol-d4 dihydrochloride is deuterated labeled Ethambutol dihydrochloride. Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity.
Product Specifications
Product Name Alternative
Emb-d4 dihydrochloride
UNSPSC
12352211
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
CCC(CO)NC([2H])([2H])C([2H])([2H])NC(CO)CC.Cl.Cl
Molecular Formula
C10H22D4Cl2N2O2
Molecular Weight
281.26
References & Citations
[1]Ethambutol. Tuberculosis (Edinb), 2008. 88 (2) : p. 102-5.|[2]Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33 (3) : p. 167-75.|[3]Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17 (1) : p. 51-5.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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