Ethacrynic acid (Standard)
Ethacrynic acid (Standard) is the analytical standard of Ethacrynic acid. This product is intended for research and analytical applications. Ethacrynic acid (Etacrynic acid) is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs) . Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4].
Product Specifications
CAS Number
58-54-8
Product Name Alternative
Etacrynic acid (Standard)
UNSPSC
12352005
Hazard Statement
H302
Target
Calcium Channel; Glutathione S-transferase; NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ethacrynic-acid-standard.html
Purity
98.78
Smiles
O=C(O)COC1=CC=C(C(C(CC)=C)=O)C(Cl)=C1Cl
Molecular Formula
C13H12Cl2O4
Molecular Weight
303.14
Precautions
H302
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched
Isoform
L-type calcium channel
Available Sizes
Frequently Asked Questions
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