Cathepsin L Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
Abbreviation
Cathepsin L
UniProt
P07711
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Cathepsin L protein expressed by Mammalian
Target
CATL; CATL1; CTSL; CTSL1; Cathepsin L1; Cathepsin L1 light chain; CathepsinL; FLJ31037; MEP; MGC123162; Major excreted protein; cathepsin L; cb15; ctsl1b; hgg1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:500-1:1000
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/eyqaid
Product MSDS
https://789.bio/ea/eyqaiD
Isotype
IgG
Available Sizes
Curated Selection
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