(Rac) -Cl-amidine
(Rac) -Cl-amidine is an orally active peptidyl arginine deimidase (PAD) inhibitor with the property of inhibiting PAD activity. (Rac) -Cl-amidine exhibits enhanced efficacy in cells and can be used to study PAD function. (Rac) -Cl-amidine can effectively regulate gene transcription, cell differentiation and innate immune response[1].
Product Specifications
CAS Number
1965308-76-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rac-cl-amidine.html
Smiles
C(CCC(C(=O)N)NC(=O)C1=CC=CC=C1)NC(CCl)=N
Molecular Formula
C14H19ClN4O2
Molecular Weight
310.78
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]The development of N-α- (2-carboxyl) benzoyl-N (5) - (2-fluoro-1-iminoethyl) -l-ornithine amide (o-F-amidine) and N-α- (2-carboxyl) benzoyl-N (5) - (2-chloro-1-iminoethyl) -l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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