Folinic acid (calcium salt pentahydrate)
Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity[1].
Product Specifications
CAS Number
[6035-45-6]
Product Name Alternative
Leucovorin (calcium salt pentahydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antifolate; Endogenous Metabolite
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Folinic-acid-calcium-salt-pentahydrate.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL|H2O : 10 mg/mL (ultrasonic)
Smiles
O=CN1C(C2=O)=C(NC(N)=N2)NCC1CNC3=CC=C(C(N[C@H](C([O-])=O)CCC([O-])=O)=O)C=C3.O.O.O.O.[Ca+2].O
Molecular Formula
C20H31CaN7O12
Molecular Weight
601.58
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Citation 01
Available Sizes
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