PqsR/LasR-IN-1
Product Specifications
UNSPSC Description
PqsR/LasR-IN-1 (compound 2a) is a potent PqsR and LasR systems inhibitor. PqsR/LasR-IN-1 has anti-virulence activity against Pseudomonas aeruginosa. PqsR/LasR-IN-1 can reduce production of biofilm, pyocyanin, and rhamnolipids in PA[1].
Target Antigen
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pqsr-lasr-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C(C=C(C=C1)NC(C2=CC3=C(C(OC(C3)C4=CC=C(C=C4)Cl)=O)C=C2)=O)C
Molecular Weight
405.87
References & Citations
[1]Mohammad Anwar Hossain, et al. Design, synthesis, and evaluation of compounds capable of reducing <i>Pseudomonas aeruginosa</i> virulence. Eur J Med Chem. 2020 Jan 1;185:111800.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146327/PqsR-LasR-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146327/PqsR-LasR-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
924818-33-7
Available Sizes
Curated Selection
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