AXKO-0046
AXKO-0046, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor.AXKO-0046 has LDHB inhibitory activity with an EC50 value of 42 nM.AXKO-0046 can be used for the research of cancer metabolism[1].
Product Specifications
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/axko-0046.html
Purity
99.77
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(NCC(N2)=C(CCNCC3=CC=CC=C3)C4=C2C=CC=C4)CCCCCC1
Molecular Formula
C25H33N3
Molecular Weight
375.55
References & Citations
[1]Sachio Shibata, et al. Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep. 2021 Nov 1;11 (1) :21353.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHB
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![PE Anti-Mouse CD14 Antibody[Sa14-2]](https://cdn.genprice.uk/products/763/68dd14b0061270361e7d3d1f/imageurl/e-ab-f1176d.webp)
