MOR agonist-4
Product Specifications
UNSPSC Description
MOR agonist-4 (2d) is a G protein signaling-biased Kappa opioid receptor (KOR) agonist with an EC50 value of 11 nM. MOR agonist-4 contains an electron withdrawing CF3 group and a bias factor of 38 based on triazole. MOR agonist-4 is used in the research of pruritis and analgesia[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mor-agonist-4.html
Smiles
CC(C=C1)=C(C(F)(F)F)C=C1CCC(N2CC3=CC=CS3)=NN=C2C4=CC=CC=N4
Molecular Weight
428.47
References & Citations
[1]Trojniak AE, et al. Synthesis and evaluation of 3,4,5-trisubstituted triazoles as G protein-biased kappa opioid receptor agonists[J]. Eur J Med Chem. 2024 Jun 27;276:116627.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161812/MOR-agonist-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161812/
Clinical Information
No Development Reported
CAS Number
3050669-97-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
