Stichodactyla Toxin

<strong>Stichodactyla Toxin</strong> <strong>Catalog number:</strong> MDP0658 <strong>CAS Number: </strong>N/A <strong>Sequence: </strong>Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (Reported disulfide bonds between Cys3-Cys35, Cys12-Cys28, and Cys17-Cys32) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 4054.8 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Madio B, Undheim EAB, King GF. Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus J Proteomics. 2017 Aug 23;166:83-92. 2: Chang SC, Huq R, Chhabra S, Beeton C, Pennington MW, Smith BJ, Norton RS. N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3 FEBS J. 2015 Jun;282(12):2247-59. 3: Celedón G, González G, Gulppi F, Pazos F, Lanio ME, Alvarez C, Calderón C, Montecinos R, Lissi E. Effect of human serum albumin upon the permeabilizing activity of sticholysin II, a pore forming toxin from Stichodactyla heliantus Protein J. 2013 Dec;32(8):593-600. 4: Chi V, Pennington MW, Norton RS, Tarcha EJ, Londono LM, Sims-Fahey B, Upadhyay SK, Lakey JT, Iadonato S, Wulff H, Beeton C, Chandy KG. Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases Toxicon. 2012 Mar 15;59(4):529-46. 5: García-Montoya C, Heras-Márquez D, Amigot-Sánchez R, García-Linares S, Martínez-Del-Pozo Á, Palacios-Ortega J. Sticholysin recognition of ceramide-phosphoethanolamine Arch Biochem Biophys. 2023 Jul 1;742:109623. 6: Celedón G, González G, Lissi E, Cerda T, Martinez D, Soto C, Pupo M, Pazos F, Lanio ME, Alvarez C. Effect of calcium on the hemolytic activity of Stichodactyla helianthus toxin sticholysin II on human erythrocytes Toxicon. 2009 Nov;54(6):845-50. 7: Castañeda O, Sotolongo V, Amor AM, Stöcklin R, Anderson AJ, Harvey AL, Engström A, Wernstedt C, Karlsson E. Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus Toxicon. 1995 May;33(5):603-13. 8: Hervis YP, Valle A, Dunkel S, Klare JP, Canet L, Lanio ME, Alvarez C, Pazos IF, Steinhoff HJ. Architecture of the pore forming toxin sticholysin I in membranes J Struct Biol. 2019 Oct 1;208(1):30-42. 9: Ashwood LM, Elnahriry KA, Stewart ZK, Shafee T, Naseem MU, Szanto TG, van der Burg CA, Smith HL, Surm JM, Undheim EAB, Madio B, Hamilton BR, Guo S, Wai DCC, Coyne VL, Phillips MJ, Dudley KJ, Hurwood DA, Panyi G, King GF, Pavasovic A, Norton RS, Prentis PJ. Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family BMC Biol. 2023 May 24;21(1):121. <a href="https://pubmed.ncbi.nlm.nih.gov/33255441">10: Rivera-de-Torre E, Palacios-Ortega J, Slotte JP, Gavilanes JG, Martínez-Del-Pozo Á, García-Linares S. Functional and Structural Variation among Sticholysins, Pore-Forming Proteins from the Sea Anemone Stichodactyla helianthus Int J Mol Sci. 2020 Nov 24;21(23):8915. </a> <br><strong>Products Related to Stichodactyla Toxin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>