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Simurosertib

Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of [1].

Product Specifications

CAS Number

1330782-76-7

Product Name Alternative

TAK-931

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/TAK-931.html

Purity

99.94

Solubility

DMSO : 70 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(C=C(C3=CNN=C3C)S2)NC([C@H]4N(CC5)CCC5C4)=N1

Molecular Formula

C17H19N5OS

Molecular Weight

341.43

References & Citations

[1]K Iwai, et al. A novel CDC7-selective inhibitor TAK-931 with potent antitumor activity. European Journal of Cancer , 2016 , 69 (1) :S34.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

CDC

Available Sizes

Frequently Asked Questions

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