BDE 47 (Standard)
BDE 47 (Standard) is the analytical standard of BDE 47. This product is intended for research and analytical applications. BDE 47 targets mitochondria, inhibits mitochondrial oxidative phosphorylation (OXPHOS), decreases mitochondrial membrane potential (MMP) and induces apoptosis in embryonic cell. BDE 47 induces the generation of ROS, and activates the JNK signaling pathway. BDE 47 exhibits embryonic developmental toxicity in zebrafish[1].
Product Specifications
CAS Number
5436-43-1
UNSPSC
12352005
Target
Apoptosis; JNK; Oxidative Phosphorylation; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bde-47-standard.html
Smiles
BrC1=CC=C(C(Br)=C1)OC2=CC=C(C=C2Br)Br
Molecular Formula
C12H6Br4O
Molecular Weight
485.79
References & Citations
[1]Zhuang J, et al., BDE-47 induced apoptosis in zebrafish embryos through mitochondrial ROS-mediated JNK signaling. Chemosphere. 2020 Nov;258:127385.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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