Camalexin

Camalexin is a phytoalexin isolated from Camelina sativa (Cruciferae) with antibacterial, antifungal, antiproliferative and anticancer activities. Camalexin can induce reactive oxygen species (ROS) production[1][2][3].

Product Specifications

CAS Number

[135531-86-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Fungal; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/camalexin.html

Purity

99.70

Solubility

DMSO : 175 mg/mL (ultrasonic)

Smiles

C12=C(C=CC=C2)NC=C1C3=NC=CS3

Molecular Formula

C11H8N2S

Molecular Weight

200.26

Precautions

H302, H315, H319, H335

References & Citations

[1]William A.Ayer, et al. Synthesis of camalexin and related phytoalexins. Tetrahedron. Volume 48, Issue 14, 1992, Pages 2919-2924.|[2]Glawischnig E. Camalexin. Phytochemistry. 2007 Feb;68 (4) :401-6.|[3]Mezencev R, et al. Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers. Neoplasma. 2003;50 (4) :239-45.