Human Hsp90 Alpha

<strong>Human Hsp90 Alpha</strong>_x000D_ <strong>Catalog number:</strong> B2013163_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 86.8 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Recombinant Human Hsp90 alpha_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wu Z, Geng Y, Lu X, Shi Y, Wu G, Zhang M, Shan B, Pan H, Yuan J. Chaperone-mediated autophagy is involved in the execution of ferroptosis Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2996-3005._x000D_ 2: LaPointe P, Mercier R, Wolmarans A. Aha-type co-chaperones: the alpha or the omega of the Hsp90 ATPase cycle? Biol Chem. 2020 Mar 26;401(4):423-434._x000D_ 3: Semenza GL. Hypoxia-inducible factor 1 (HIF-1) pathway Sci STKE. 2007 Oct 9;2007(407):cm8._x000D_ 4: Mirhadi E, Roufogalis BD, Banach M, Barati M, Sahebkar A. Resveratrol: Mechanistic and therapeutic perspectives in pulmonary arterial hypertension Pharmacol Res. 2021 Jan;163:105287._x000D_ 5: Zubrienė A, Gutkowska M, Matulienė J, Chaleckis R, Michailovienė V, Voroncova A, Venclovas C, Zylicz A, Zylicz M, Matulis D. Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms Biophys Chem. 2010 Nov;152(1-3):153-63._x000D_ 6: Hoy SM. Pimitespib: First Approval Drugs. 2022 Sep;82(13):1413-1418._x000D_ 7: Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW. Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol FEBS J. 2007 Sep;274(17):4453-63._x000D_ 8: Bohush A, Filipek A. HSP90 Co-Chaperone, CacyBP/SIP, Protects α-Synuclein from Aggregation Cells. 2020 Oct 8;9(10):2254._x000D_ 9: Henot F, Crublet E, Frech M, Boisbouvier J. NMR assignment of human HSP90 N-terminal domain bound to a long residence time resorcinol ligand Biomol NMR Assign. 2022 Oct;16(2):257-266._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34137356">10: Usman M, Ilyas A, Syed B, Hashim Z, Ahmed A, Zarina S. Serum HSP90-Alpha and Oral Squamous Cell Carcinoma: A Prospective Biomarker Protein Pept Lett. 2021;28(10):1157-1163. </a>_x000D_ _x000D_ <strong>Products Related to Human Hsp90 Alpha can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>