MDPR-Val-Cit-PAB-MMAE (TFA)
MDPR-Val-Cit-PAB-MMAE TFA is a drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC), consisting of a tubulin polymerization inhibitor MMAE and an ADC linker (peptide Val-Cit- PAB) composition[1].
Product Specifications
CAS Number
2185872-76-6
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdpr-val-cit-pab-mmae-tfa.html
Purity
99.51
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N4C(C=CC4=O)=O)CN)=O)=O)=O)C=C3)=O)C)=O)=O)C.O=C(O)C(F)(F)F
Molecular Formula
C67H101F3N12O17
Molecular Weight
1403.58
References & Citations
[1]Moquist, et al. Preparation of drug conjugates of IgG1 antibodies with self-stabilizing linkers having improved physiochemical properties for treating cancers and autoimmune diseases. World Intellectual Property Organization, WO2018031690 A1. 2018-02-15.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740029-100 1x 100 µL
Fibronectin (TV-1), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNCB0705-100 1x 100 µL
MART-1 / Melan-A (M2-7C10 + M2-9E3), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941010-500 1x 500 µL
Cytochrome C (CYCS/1010), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione](https://cdn.genprice.uk/products/572/55803271245/imageurl/trc-d493755-25mg.webp)
TRC-D493755-25MG 25 mg
7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione
Sign In for Pricing
View Details