Oxindole
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
Product Specifications
CAS Number
59-48-3
Product Name Alternative
2-Indolinone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; HIV
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection; Endocrinology; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/NSC_274863.html
Purity
99.61
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1NC2=C(C=CC=C2)C1
Molecular Formula
C8H7NO
Molecular Weight
133.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Leoni A, et al. 2-Indolinone a versatile scaffold for treatment of cancer: a patent review (2008-2014) . Expert Opin Ther Pat. 2016;26 (2) :149-73.|[2]Kaur M, et al. Oxindole: A chemical prism carrying plethora of therapeutic benefits. Eur J Med Chem. 2016 Nov 10;123:858-894.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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