PDZK1 Recombinant Rabbit Monoclonal Antibody [JE37-70]

Na (+)/H (+) exchange regulatory cofactor NHE-RF3 is a protein that in humans is encoded by the PDZK1 gene. This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

1700023D20Rik antibody 2610507N21Rik antibody 4921513F16Rik antibody AI267131 antibody AI314638 antibody AL022680 antibody C terminal linking and modulating protein antibody CAP70 antibody CFTR associated protein of 70 kDa antibody CFTR associated protein, 70-KD antibody CFTR-associated protein of 70 kDa antibody CLAMP antibody D3Ertd537e antibody Dietary Pi-regulated RNA-1 antibody Diphor-1 antibody mPDZK1 antibody Na (+)/H (+) exchange regulatory cofactor NHE-RF3 antibody Na (+)/H (+) exchanger regulatory factor 3 antibody Na/Pi cotransporter C-terminal-associated protein 1 antibody Na/Pi cotransporter C-terminal-associated protein antibody NaPi Cap1 antibody NaPi-Cap1 antibody NaPiCap1 antibody NHERF 3 antibody NHERF-3 antibody NHERF3 antibody NHRF3_HUMAN antibody OTTHUMP00000015572 antibody PDZ domain containing 1 antibody PDZ domain containing protein 1 antibody PDZ domain-containing protein 1 antibody PDZD1 antibody PDZK1 antibody Sodium hydrogen exchanger regulatory factor 3 antibody Sodium-hydrogen exchanger regulatory factor 3 antibody

Abbreviation

PDZK1, CAP70, NHERF3, PDZD1

Swiss Prot

Q5T2W1 Human

Cellular Locus

Membrane, Cell membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within

Isotype

IgG

Clone

JE37-70

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP

Positive Control

Caco-2 cell lysate, Human liver tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 57 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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