Synstatin (92-119)
Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion. Synstatin (92-119) down-regulates integrin α β3 and reduces the activation of angiogenic growth factors VEGF and FGF-2[1][2].
Product Specifications
CAS Number
1259384-47-8
Product Name Alternative
SSTN92-119
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/synstatin-92-119.html
Purity
99.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CCC1)C([C@@H](N)CC(C)C)=O)N[C@@H](C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCC(O)=O)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N4[C@@H](CCC4)C(NCC(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C133H207N35O46
Molecular Weight
3032.27
References & Citations
[1]Metwaly HA, et al. Inhibition of the signaling pathway of syndecan-1 by synstatin: A promising anti-integrin inhibitor of angiogenesis and proliferation in HCC in rats. Arch Biochem Biophys. 2018 Aug 15;652:50-58.|[2]Rapraeger AC. Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis. FEBS J. 2013 May;280 (10) :2207-15.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15135143 1 Vial
Lentiviral human SERTAD2 shRNA (UAS) - Lentiviral human SERTAD2 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details 