Ferroptosis-IN-15
Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells and 786-O cells, respectively.Ferroptosis-IN-15 is a potential iron chelator and radical trapping antioxidant[1].
Product Specifications
CAS Number
1260669-24-6
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ferroptosis-in-15.html
Smiles
O=C1OCC(CC2=CC(O)=C(O)C=C2)=C1C3=CC=C(O)C=C3
Molecular Formula
C17H14O5
Molecular Weight
298.29
References & Citations
[1]Zheng-Biao Zou, et al. Nigenolides A–H, 13 new microperfuranones with ferroptosis inhibitory activity from the deep-sea-derived Aspergillus niger. Bioorganic Chemistry Volume 153, December 2024, 107919
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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