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Ferroptosis-IN-15

Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells and 786-O cells, respectively.Ferroptosis-IN-15 is a potential iron chelator and radical trapping antioxidant[1].

Product Specifications

CAS Number

1260669-24-6

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ferroptosis-in-15.html

Smiles

O=C1OCC(CC2=CC(O)=C(O)C=C2)=C1C3=CC=C(O)C=C3

Molecular Formula

C17H14O5

Molecular Weight

298.29

References & Citations

[1]Zheng-Biao Zou, et al. Nigenolides A–H, 13 new microperfuranones with ferroptosis inhibitory activity from the deep-sea-derived Aspergillus niger. Bioorganic Chemistry Volume 153, December 2024, 107919

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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