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(S) - (+) -Ibuprofen (Standard)

(S) - (+) -Ibuprofen (Standard) is the analytical standard of (S) - (+) -Ibuprofen. This product is intended for research and analytical applications. (S) - (+) -Ibuprofen ((S) -Ibuprofen), a S (+) -enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM, respectively. (S) - (+) -Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects[1][2].

Product Specifications

CAS Number

51146-56-6

Product Name Alternative

Dexibuprofen (Standard)

UNSPSC

12352005

Target

COX; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/s-plus-ibuprofen-standard.html

Purity

99.87

Smiles

OC([C@H](C1=CC=C(CC(C)C)C=C1)C)=O

Molecular Formula

C13H18O2

Molecular Weight

206.28

References & Citations

[1]Evans AM, et al. Comparative pharmacology of S (+) -ibuprofen and (RS) -ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14.|[2]N Scheuren, et al. Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br J Pharmacol. 1998 Feb;123 (4) :645-52.|[3]Astrid Janssen, et al. Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. Eur J Pharmacol. 2006 Jul 1;540 (1-3) :24-33.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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