Estradiol cypionate

Estradiol cypionate is the 17β-cypionate ester of Estradiol, which inhibits ET-1 synthesis by acting on estrogen receptors[1].

Product Specifications

CAS Number

[313-06-4]

UNSPSC

12352005

Hazard Statement

H302, H312, H332, H350, H360

Target

Apoptosis; Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Apoptosis; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Estradiol-cypionate.html

Purity

99.47

Solubility

DMSO : ≥ 30 mg/mL|Ethanol : 14.29 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@@H](OC(CCC3CCCC3)=O)CC[C@@]1([H])[C@]4([H])CCC5=C(C=CC(O)=C5)[C@@]4([H])CC2

Molecular Formula

C26H36O3

Molecular Weight

396.56

Precautions

H302, H312, H332, H350, H360

References & Citations

[1]Feng X, et al. NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. Cell Death Dis. 2017 May 11;8 (5) :e2783.|[2]Karimian E, et al. Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits. PLoS One. 2013 Jun 28;8 (6) :e67859. |[3]Sá Filho MF, et al. Impact of hormonal modulation at proestrus on ovarian responses and uterine gene expression of suckled anestrous beef cows. J Anim Sci Biotechnol. 2017 Nov 1;8:79. |[4]Qiu X, et al. Estradiol cypionate inhibits proliferation and promotes apoptosis of gastric cancer by regulating AKT ubiquitination. Biomed Pharmacother. 2023 Sep;165:115073.