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Pinaverium bromide-d4

Pinaverium bromide-d4 is deuterium labeled Pinaverium bromide. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].

Product Specifications

UNSPSC

12352005

Target

Calcium Channel; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

CC1(C)[C@@H]2CC[C@H](CCOC([2H])([2H])C([2H])([2H])[N+]3(CC4=CC(OC)=C(OC)C=C4Br)CCOCC3)[C@H]1C2.[Br-]

Molecular Formula

C26H37D4Br2NO4

Molecular Weight

595.44

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Dai Y, et al. Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. World J Gastroenterol. 2003 Mar;9 (3) :557-61.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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