Recombinant Human GSTAL Protein (Trx Tag)
Product Specifications
Background
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1) . GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.
Abbreviation
GSTAL
Synonyms
GST; GTH; GSTA; HA subunit; GST HA subunit; GST class alpha member; GST class-alpha member; Glutathione S transferase A; Glutathione S alkyltransferase A; S (hydroxyalkyl) glutathione lyase A; GSTA1; GST-epsilon; GST2; GSTA1-1; GTH1; Glutathione S alkyltransferase A1; GST class-alpha member 1; HA subunit 1; S (hydroxyalkyl) glutathione lyase A1; Glutathione S transferase A1; GST class alpha member 1; GST epsilon; GST HA subunit 1; GSTA1 1; Glutathione S transferase 2; Glutathione S transferase Ha subunit 1; GST class-alpha member 1; GST epsilon; GST HA subunit 1; GST2; GSTA1; GSTA1-1; GST-epsilon; GTH1; HA subunit 1; MGC131939
UniProt
P08263
Accession Number
P08263
Expression System
E.coli
Tag
N-Trx
Sequence
Met1-Phe222
Field of Research
Signal Transduction; Tags & Cell Markers; Metabolism
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
44.4 kDa
Observed Molecular Weight
39 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items