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Otilonium (bromide) (Standard)

Otilonium (bromide) (Standard) is the analytical standard of Otilonium (bromide) . This product is intended for research and analytical applications. Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant which can interfere with the mobilization of calcium in intestinal smooth muscle, OB can be used for research of irritable bowel syndrome[1][2][3].

Product Specifications

CAS Number

26095-59-0

Product Name Alternative

Octylonium bromide (Standard) ; SP63 (Standard)

UNSPSC

12352005

Target

MAChR; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/otilonium-bromide-standard.html

Smiles

O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-]

Molecular Formula

C29H43BrN2O4

Molecular Weight

563.57

References & Citations

[1]Battaglia, G., et al., Otilonium bromide in irritable bowel syndrome: a double-blind, placebo-controlled, 15-week study. Aliment Pharmacol Ther, 1998. 12 (10) : p. 1003-10.|[2]Gandia, L., et al., Otilonium: a potent blocker of neuronal nicotinic ACh receptors in bovine chromaffin cells. Br J Pharmacol, 1996. 117 (3) : p. 463-470.|[3]Lindqvist S, et al. The colon-selective spasmolytic otilonium bromide inhibits muscarinic M (3) receptor-coupled calcium signals in isolated human colonic crypts. Br J Pharmacol. 2002 Dec;137 (7) :1134-42.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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