DR3 (Wsl-1, Apo-3, TRAMP, LARD1-5, Death Receptor3) (APC)

Recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3).DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95).The ligand for DR3 has very recently been identified and has been termed Apo-3L.DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD and functionally induces apoptosis and NF-KB activation.