Rat IFN-alpha/beta R2 Protein, His Tag
Interferon alpha/beta receptor 2 (IFR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFBR and IFRB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFR2 can associate with IFR1 to form the type I interferon receptor. IFR2 is a receptor for interferons alpha and beta.IFR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFR2 influence susceptibility to hepatitis B virus (HBV) infection.
Product Specifications
Background
Specifications
Accession Number
M0R8H7-1
Expression Region
Phe 31 - Ala 244
Host
HEK293
Target
IFN-alpha/beta R2
Conjugation
Unconjugated
Tag
C-10xHis
Source
Rat
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
26.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Host or Source
HEK293
Species
Rat
Protein ID
M0R8H7-1
Preservative
Trehalose
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