What is the catalog number for ITE?

The catalog number for ITE is HY-19317.

What sizes are available for ITE?

ITE is available in the following size(s): 1 mg, 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does ITE come in?

ITE is available in 7 different pack sizes.

ITE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ITE?

ITE is manufactured by QuantiMol.

What is the estimated delivery time for ITE?

Estimated delivery time for ITE is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ITE?

The safety data sheet for ITE is available here: http://file.medchemexpress.com/batch_PDF/HY-19317/ITE-SDS-MedChemExpress.pdf.

ITE

ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.

Product Specifications

CAS Number

448906-42-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/ITE.html

Concentration

10mM

Purity

99.27

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(C1=CSC(C(C2=CNC3=C2C=CC=C3)=O)=N1)OC

Molecular Formula

C14H10N2O3S

Molecular Weight

286.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Song J, et al. A ligand for the aryl hydrocarbon receptor isolated from lung. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :14694-9.|[2]Nugent LF, et al. ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity. Invest Ophthalmol Vis Sci. 2013 Nov 13;54 (12) :7463-9.|[3]Pang LP, et al. ITE inhibits growth of human pulmonary artery endothelial cells. Exp Lung Res. 2017 Oct;43 (8) :283-292.