Remdesivir O-desphosphate acetonide impurity
Product Specifications
UNSPSC Description
Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].
Target Antigen
DNA/RNA Synthesis; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/remdesivir-o-desphosphate-acetonide-impurity.html
Smiles
N#C[C@](O1)(C2=CC=C3N2N=CN=C3N)[C@@](OC4(C)C)([H])[C@@](O4)([H])[C@H]1CO
Molecular Weight
331.332
References & Citations
[1]Dustin Siegel, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017 Mar 9;60(5):1648-1661.|[2]Manli Wang, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136597/Remdesivir-O-desphosphate-acetonide-impurity-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136597/Remdesivir-O-desphosphate-acetonide-impurity-SDS-MedChemExpress.pdf
CAS Number
1191237-80-5
Available Sizes
Curated Selection
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