Recombinant CDKN2B Protein

<strong>Recombinant CDKN2B Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017483_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 41.55 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Cyclin dependent kinase Inhibitor 2B, MTS2, INK4B, CDK4I, TP15, P15, P15 CDK Inhibitor_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Goethe EA, Youssef M, Patel AJ, Jalali A, Goodman JC, Mandel JJ. Recurrent Papillary Glioneuronal Tumor World Neurosurg. 2019 Aug;128:127-130._x000D_ 2: Tawarayama H, Feng Q, Murayama N, Suzuki N, Nakazawa T. Cyclin-Dependent Kinase Inhibitor 2b Mediates Excitotoxicity-Induced Death of Retinal Ganglion Cells Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4479-4488._x000D_ 3: Gao P, Si J, Yang B, Yu J. Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B) Med Sci Monit. 2017 Feb 18;23:881-888._x000D_ 4: Feng A, Li Y, Li G, Wang Y, Wen Q, Yang Z, Tian K, Lv H, Guo L, Zhang S, Liu X, Jiang D. Genomic Features of Organ-Specific Metastases in Lung Adenocarcinoma Front Oncol. 2022 Jul 14;12:908759._x000D_ 5: Nanda V, Downing KP, Ye J, Xiao S, Kojima Y, Spin JM, DiRenzo D, Nead KT, Connolly AJ, Dandona S, Perisic L, Hedin U, Maegdefessel L, Dalman J, Guo L, Zhao X, Kolodgie FD, Virmani R, Davis HR Jr, Leeper NJ. CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels Circ Res. 2016 Jan 22;118(2):230-40._x000D_ 6: Wu DT, Bitzer M, Ju W, Mundel P, Böttinger EP. TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes J Am Soc Nephrol. 2005 Nov;16(11):3211-21._x000D_ 7: Aesoy R, Gradin K, Aasrud KS, Hoivik EA, Ruas JL, Poellinger L, Bakke M. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways Mol Cancer. 2014 Mar 11;13:54._x000D_ 8: Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10._x000D_ 9: Zhang CS, Xu JX, Deng FH, Hu HL, Wang SQ, Huang H, Wei SX. [Effect of Down-Regulation of ANRIL on Proliferation and Apoptosis of Kasumi-1 Cells and Its Potential Mechanism] Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022 Aug;30(4):984-989._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34225755">10: Liu L, Chen Y, Huang Y, Cao K, Liu T, Shen H, Cui J, Li B, Cai J, Gao F, Yang Y. Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance Mol Cancer. 2021 Jul 5;20(1):94. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant CDKN2B Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>