Dihydrokainic acid
Dihydrokainic acid is a glutamate transporters (especially GLT1) inhibitor. Dihydrokainic acid targets GLT1 with high affinity, effectively inhibiting its transport function. Dihydrokainic acid exerts its effect by inhibiting the uptake of glutamate, leading to an increase in extracellular glutamate concentration, thereby affecting neuronal excitability and neurotransmission. Dihydrokainic acid is mainly applied in the field of neuroscience for research on glutamate-related neural functions, epilepsy, learning, and memory[1][2][3][4][5].
Product Specifications
CAS Number
52497-36-6
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dihydrokainic-acid.html
Purity
99.0
Solubility
H2O : 5 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)C
Molecular Formula
C10H17NO4
Molecular Weight
215.25
Precautions
H302, H312, H332
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EAAT2
Available Sizes
Frequently Asked Questions
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