What is the catalog number for Apilimod?

The catalog number for Apilimod is HY-14644.

What sizes are available for Apilimod?

Apilimod is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg.

How many pack sizes does Apilimod come in?

Apilimod is available in 7 different pack sizes.

Is Apilimod in stock?

Apilimod is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Apilimod?

Apilimod is manufactured by QuantiMol.

What is the estimated delivery time for Apilimod?

Estimated delivery time for Apilimod is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Apilimod?

The safety data sheet for Apilimod is available here: http://file.medchemexpress.com/batch_PDF/HY-14644/Apilimod-SDS-MedChemExpress.pdf.

Apilimod

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor.

Product Specifications

CAS Number

541550-19-0

Product Name Alternative

STA 5326; LAM-002A (free base) ; AIT-101

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Interleukin Related; PIKfyve

Type

Reference compound

Related Pathways

Immunology/Inflammation; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Apilimod.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1

Molecular Formula

C23H26N6O2

Molecular Weight

418.49

Precautions

H315, H319, H335

References & Citations

[1]Wada Y, et al. Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood. 2007 Feb 1;109 (3) :1156-64.|[2]Keino H, et al. Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis. Arthritis Res Ther. 2008;10 (5) :R122.