6-Hydroxy-1- (4- (2-hydroxyethyl) piperazin-1-yl) hexan-1-one
6-Hydroxy-1- (4- (2-hydroxyethyl) piperazin-1-yl) hexan-1-one is the linker for PROTAC METTL3-14 degrader 1 (HY-162282) [1].
Product Specifications
CAS Number
[2859434-39-0]
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-hydroxy-1-4-2-hydroxyethyl-piperazin-1-yl-hexan-1-one.html
Smiles
O=C(CCCCCO)N(CC1)CCN1CCO
Molecular Formula
C12H24N2O3
Molecular Weight
244.33
References & Citations
[1]Francesco Errani, et al. Proteolysis Targeting Chimera Degraders of the METTL3-14 m6A-RNA Methyltransferase. JACS Au. 2024 Feb 12;4 (2) :713-729.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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