1-beta-D-Arabinofuranosyluracil

1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties[1]. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells[2].

Product Specifications

CAS Number

[3083-77-0]

Product Name Alternative

Uracil 1-β-D-arabinofuranoside

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/1-beta-d-arabinofuranosylurac-il.html

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)=O

Molecular Formula

C9H12N2O6

Molecular Weight

244.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Bertin MJ, et al. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. J Nat Prod. 2015 Mar 27;78 (3) :493-9.|[2]Müller WE, et al. Metabolism of 1-beta-D-arabinofuranosyluracil in mouse L5178Y cells. Cancer Res. 1979 Mar;39 (3) :1102-7.