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HSPB1 antibody

Product Specifications

Background

HSPB1, also known as heat shock protein 27 (Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed. (21353161)

Synonyms

Heat shock protein beta-1 (HspB1) |28 kDa heat shock protein|Estrogen-regulated 24 kDa protein|Heat shock 27 kDa protein (HSP 27) |Stress-responsive protein 27 (SRP27) |HSPB1|HSP27|HSP28

UniProt

P04792

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Heat shock 27kDa protein 1

Target

HSPB1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Neuroscience, Immunology, Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:3000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

19-27 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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