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HSPB1 antibody

Product Specifications

Background

HSPB1, also known as heat shock protein 27(Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed.(21353161)

Synonyms

Heat shock protein beta-1 (HspB1)|28 kDa heat shock protein|Estrogen-regulated 24 kDa protein|Heat shock 27 kDa protein (HSP 27)|Stress-responsive protein 27 (SRP27)|HSPB1|HSP27|HSP28

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

heat shock 27kDa protein 1

Target

HSPB1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:3000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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