Antineoplaston A10

Antineoplaston A10 is an antineoplaston that inhibits the growth of human hepatoma cells by inducing apoptosis. Antineoplaston A10 can be used in the study of liver cancer and breast cancer[1][2].

Product Specifications

CAS Number

[91531-30-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bcl-2 Family; Endogenous Metabolite; MDM-2/p53

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antineoplaston-a10.html

Purity

99.84

Solubility

DMSO : 175 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](CC1)C(NC1=O)=O)CC2=CC=CC=C2

Molecular Formula

C13H14N2O3

Molecular Weight

246.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Qu XJ, et al. Induction of apoptosis in human hepatocellular carcinoma cells by synthetic antineoplaston A10. Anticancer Res. 2007 Jul-Aug;27 (4B) :2427-31.|[2]Tsuda, et al. "Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines." The Kurume Medical Journal 37.2 (1990) : 97-104.