Desthiobiotin-Iodoacetamide
Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004) -treated cell lysis[1].
Product Specifications
CAS Number
[2924824-04-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/desthiobiotin-iodoacetamide.html
Purity
99.51
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ICC(NCCNC(CCCCC[C@H]1NC(N[C@H]1C)=O)=O)=O
Molecular Formula
C14H25IN4O3
Molecular Weight
424.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang Y, et al. Oridonin acts as a novel senolytic by targeting glutathione S-transferases to activate the ROS-p38 signaling axis in senescent cells. Chem Commun (Camb) . 2022 Nov 29;58 (95) :13250-13253.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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